姓名 |
陈正礼 |
政治面貌 |
民盟 |
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导师类型 |
硕导/博导 |
办公地点 |
6-107 |
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职称/职务 |
教授/院教代会主席 |
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电子邮箱 |
chzhli75@163.com |
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研究方向 |
动物比较医学、实验动物疾病模型的构建和应用 |
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学术、技术组织任职/头衔 |
中国动物解剖及组织胚胎学分会,常务理事中国动物病理学家委员会,委员中国实验动物学会,会员四川省灵长类学会,会员 |
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教育背景及工作经历 |
1998年,四川畜牧兽医学院,获学士学位; 2001年,西北农林科技大学,获硕士学位; 2004年,西北农林科技大学,获博士学位; 2004年至今,yl34511线路中心,任教2008年,yl34511线路中心,副教授2012年,yl34511线路中心,教授 |
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教学课程 |
动物解剖学、实验动物学、专业概论与新生研讨 |
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人才培养情况 |
培养毕业硕士研究生30名,在读博士生3名,硕士生8名 |
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科研项目(近五年) |
1.四川省科技厅, 四川省国际科技创新合作/港澳台科技创新合作目,2020YFH0148,基于MPTP诱导帕金森猕猴模型探究氯碘羟喹药效及其作用机制, 2020-01至 2022-12,主持 2.国家重大科学仪器设备开发专项:MSFRI在视网膜疾病猕猴繁育与动物模型评价中的应用(2013YQ49085906),2013.10-2018.09,主持 3.国家科技支撑计划:灵长类动物人类重大疾病模型的研究与示范(子课题)(2014BAI03B01),2013-2017,主持 4.国家自然科学基金,面上项目, 32071161,氧化防御基因LanCL1对帕金森病的保护及其在神经元蛋白质谷胱甘肽化中的作用研究, 2021-2024,主研 5.国家自然科学基金, 面上项目, 31871179,下丘脑LanCL1蛋白及氧化应激在高脂饮食诱导肥胖发生中的作用及机理研究, 2019-2022,主研 |
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主要论著、代表性论文 |
1.Chao Huang, Chengcheng Yang, Dejiang Pang, Chao Li, Huan Gong, Xiyue Cao, Xia He, Xueyao Chen, Bin Mu, Yiyuan Cui , Wentao Liu, Qihui Luo, Anchun Cheng, Lanlan Jia, Mina Chen , Bo Xiao and Zhengli Chen.Animal models of male subfertility targeted on LanCL1-regulated spermatogenic redox homeostasis. Lab Animal, 2022, 51, 1-13 (Cover Article, 1区TOP,IF=12.625). 2. Chao Huang, Huan Gong, Bin Mu, Xinting Lan, Chengcheng Yang, Jinlong Tan, Wentao Liu, Yuanfeng Zou, Lixia Li, Bin Feng, Xia He, Qihui Luo and Zhengli Chen.BAF-L Modulates Histone-to-Protamine Transition during Spermiogenesis." International Journal of Molecular Sciences, 2022, 23, 1985(2区TOP,IF=5.924) 3. Liangqin Shi, Yazhou Lin, Yucheng Jiao, Seth A. Herr, Jonathan Tang, Edmond Rogers, Zhengli Chen, Riyi Shi. Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1. Translational Neurodegeneration, 2021,10:13(1区TOP,IF=8.014). 4.QihuiLuo,XinyuLei, JingXu, AsadJahangir, JunboHe, ChaoHuang, WentaoLiu, AnchunCheng,LiTang, YiGeng, ZhengliChen. An altered gut microbiota in duck-origin parvovirus infection on cherry valley ducklings is associated with mucosal barrier.Poultry Science, 2021,100(4):101021(2区TOP,IF=3.352). 5. Qihui Luo, Chengjie Lao, Chao Huang, Yu Xia, Wenjing Ma, Wentao Liu, Zhengli Chen. Iron Overload Resulting from the Chronic Oral Administration of Ferric Citrate Impairs Intestinal Immune and Barrier in Mice. Biological Trace Element Research, 2021, 199:1027–1036. 6. Liangqin Shi, Chao Huang, Qihui Luo, Yu Xia, Wentao Liu, Wen Zeng, Anchun Cheng, Riyi Shi, Chen Zhengli. Clioquinol improves motor and non-motor deficits in MPTP-induced monkey model of Parkinson’s disease through AKT mTOR pathway. Aging-US, 2020,12(10):9515-9533. 7. Liangqin Shi, Chao Huang, Qihui Luo, Edmond Rogers, Yu Xia, Wentao Liu, Wenjing Ma,Wen Zeng, Li Gong, Jing Fang, Li Tang, Anchun Cheng, Riyi Shi, Zheng-li Chen.The association of iron and the pathologies of Parkinson’s diseases in MPTP/MPP+-induced neuronal degeneration in non-human primates and in cell culture. Frontiers in Aging Neuroscience,2019,11:215. 8. Chao Huang, Wenjing Ma, Qihui Luo, Liangqin Shi, Yu Xia, Chengjie Lao, Wentao Liu, Yuanfeng Zou, Anchun Cheng, Riyi Shi, Zhengli Chen. Iron overload resulting from the chronic oral administration of ferric citrate induces parkinsonism phenotypes in middle-aged mice. Aging-US,2019,11. 9. Dejiang Pang, Chao Li, Chengcheng Yang, Yuanfeng Zou, Bin Feng, Lixia Li, Wentao Liu, Yi Geng, Qihui Luo, Zhengli Chen, Chao Huang. Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide. Oxidative Medicine and Cellular Longevity, 2019, https://doi.org/10.1155/2019/1805635 10. Qihui Luo, Yifan Li, Chao Huang, Dongjing Cheng, Wenjing Ma, Yu Xia, Wentao Liu and Zhengli Chen. Soy Isoflavones Improve the Spermatogenic Defects in Diet-Induced Obesity Rats through Nrf2/HO-1 Pathway. Molecules,2019,24:2966 11. Jinlong Tan, Chao Huang, Qihui Luo, Wentao Liu, Dongjing Cheng, Yifan Li, Yu Xia, Chao Li, Li Tang, Jing Fang, Kangcheng Pan, Yangping Ou, Anchun Cheng and Zhengli Chen. Soy Isoflavones Ameliorate Fatty Acid Metabolism of Visceral Adipose Tissue by Increasing the AMPK Activity in Male Rats with Diet-Induced Obesity (DIO). Molecules,2019,24:2809 12. Qihui Luo, Jing Xu, Chao Huang, Xinyu Lei, Dongjing Cheng, Wentao Liu, Anchun Cheng, Li Tang, Jing Fang, Yangping Ou, Yi Geng and Zhengli Chen. Impacts of Duck-Origin Parvovirus Infection on Cherry Valley Ducklings From the Perspective of Gut Microbiota. Front. Microbiol.,2019,10:624 13. Qihui Luo, Dongjing Cheng, Chao Huang, Yifan Li, Chengjie Lao, Yu Xia, Wentao Liu, Xiaoxia Gong, Danlei Hu, Bin Li, Xue He and Zhengli Chen. Improvement of Colonic Immune Function with Soy Isoflavones in High-Fat Diet-Induced Obese Rats. Molecules,2019,24:1139 14. Jingfei Chen, Qihui Luo, Chao Huang, Wen Zeng, Ping Chen, Qi Gao, Bing Chen, Wentao Liu, Lingzhen Pan, and Zhengli Chen.Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A Comparative Study.Journal of Ophthalmology,2019,7, https://doi.org/10.1155/2019/7089342. 15. Qihui Luo, Bing Chen, Jing Xu, Wenjing Ma, Chengjie Lao, Yifan Li, Jinglong Tan, Yi Tang, Chao Huang, Wentao Liu, Zhengli Chen. Development of a SYBR Green II Real-Time Polymerase Chain Reaction for the Clinical Detection of the Duck-Origin Goose Parvovirus in China.Intervirology,2018, DOI: 10.1159/000495181. 16. Qihui Luo, Dandan Yang, Qi Qi, Chao Huang, Bing Chen, Wentao Liu, Liangqin Shi, Yu Xia, Li Tang, Jing Fang, Yangping Ou, Yi Geng, and Zhengli Chen. Role of the Death Receptor and Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells. BioMed Research International,2018,https://doi.org/10.1155/2018/5241941. 17. Qi Gao, Chengdong Wang, Desheng Li, Hemin Zhang, Linhua Deng, Caiwu Li and Zhengli Chen. A case of giant panda ovarian cancer diagnosis and histopathology. BMC Veterinary Research,2018,14:311. 18. Qihui Luo, Shanshan Chen, Juan Deng, Liangqin Shi, Chao Huang, Anchun Cheng, Wentao Liu, Jing Fang, Li Tang, Yi Geng, Zhengli Chen.Endocannabinoid hydrolase and cannabinoid receptor 1 are involved in the regulation of hypothalamus-pituitary-adrenal axis in type 2 diabetes. Metabolic Brain Disease,2018,33:1483–1492 19. Ping Chen, Qihui Luo, Chao Huang, Qi Gao, Like Li, Jingfei Chen, Bing Chen, Wentao Liu, Wen Zeng, Zhengli Chen. Pathogenesis of non-alcoholic fatty liver disease mediated by YAP. Hepatology International (2018) 12:26–36 20. Liangqin Shi, Chao Huang, Qihui Luo, Yu Xia, Heng Liu, Like Li, Wentao Liu, Wenjing Ma,Jing Fang, Li Tang, Wen Zeng, Zhengli Chen. Pilot study: Molecular risk factors fordiagnosing sporadic Parkinson’s disease based on gene expression in blood in MPTP-induced rhesus monkeys. Oncotarget[J],2017,8(62),105606-105614. 21. Like Li, Xiaolin Chen, Qihui Luo, Chao Huang, Wentao Liu, Zhengli Chen. Effects of soy isoflavones on testosterone synthetase in diet-induced obesity male rats. Int J Clin Exp Pathol 2017;10(9):9202-9212 22. Jing Hua, Xiyue Cao, Dejiang Pang, Qihui Luo, Yuanfeng Zou, Bin Feng, Lixia Li, Zhengli Chen, Chao Huang. Tumor grade related expression of neuroglobin is negatively regulated by PPARγ and confers antioxidant activity in glioma progression. Redox Biology,2017,12:682 23. Like Li, Liangqin Shi,Heng Liu, QihuiLuo, ChaoHuang, WentaoLiu, Xiaolin Chen, Wen Zeng, Zhengli Chen. Changes in blood anti-oxidation enzyme levels in MPTP-treated monkeys. Neuroscience letters, 2017,649(10):93-99 24. Qi-Hui Luo, Meng-Lu Chen, Zheng-Li Chen, Chao Huang, An-Chun Cheng, Jing Fang, Li Tang, Yi Geng. Evaluation of KIM-1 and NGAL as Early Indicators for Assessment of Gentamycin- Induced Nephrotoxicity In Vivo and In Vitro. Kidney Blood Press Res, 2016;41:911-918 25. Chao Huang, Dejiang Pang, Qihui Luo, Xiaolin Chen, Qi Gao, Liangqin Shi, Wentao Liu, Yuanfeng Zou, Lixia Li and Zhengli Chen. Soy Isoflavones Regulate Lipid Metabolism through an AKT/mTORC1 Pathway in Diet-Induced Obesity (DIO) Male Rats. Molecules, 2016, 21:586 26. Qihui Luo, Zhengli Chen, Anchun Cheng, Mingshu Wang, Jing Fang, Xi Peng, Li Tang. Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats. Front. Med. 2015, 9(1): 82–89 27. Qi-hui Luo, Meng-lu Chen, Feng-jiao Sun, Zheng-li Chen, Ming-yang Li, Wen Zeng, Li Gong, An-chun Cheng, Xi Peng, Jing Fang, Li Tang, Yi Geng. KIM-1 and NGAL as biomarkers of nephrotoxicity induced by gentamicin in rats. Mol Cell Biochem,2014,397:53–60 28. Qihui Luo, Wentao Liu, Jingyao Chen, Mingshu Wang, Wen Zeng, Zhengli Chen, Anchun Cheng. Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 diabetes. Neural Regeneration Research, 2012,7(4):302-307. 29. Zheng-li CHEN, Wen ZENG, An-chun CHENG, Qi-hui LUO, Zhan LI, Xi PENG, Jing FANG, Kang-cheng PAN, Min HE, Li TANG. Six-month repeated dose toxicity of orally administered metacavir in rhesus monkeys. Experimental and Toxicologic Pathology,2011, 63(4):379-385. 30. Shasha Zhou, Qihui Luo, Zhengli Chen, Anchun Cheng, Mingshu Wang, Dekang Zhu, Renyong Jia, Fei Liu, Xiaoyue Chen, Yi Zhou, Fengjun Bi, Zexia Yang. Isolation, identification of Streptococcus pneumoniae from infected rhesus monkeys and control efficacy. Journal of Medical Primatology,2010,39: 417-423. 31. Chen Zheng-li,Zhu Chun-mei,Luo Qi-hui,Pan Kang-cheng. Expression of estrogen receptor alpha, nerve growth factor, interleukin-2, and androgen receptor in the cerebellum of ovariectomized rats following soybean isoflavone treatment.Neural Regeneration Research,2009,4(12):965-972. 32. Zeng Wen,Cheng An-chun, Chen Zheng-li, Luo Qi-hui,Sun Yu-bo, Li Zhan,Bi Feng-jun. In Vivo Assessment of Mitochondrial Toxicity of Metacavir in Rhesus Monkeys after Three Months of Intravenous Administration. Acta Pharmacologica Sinica,2009,30(12):1666-1673. 33. CHEN Zheng-li, FAN Guang-li, LUOQi-hui, ZHUChun-mei, HUANGYi-dan. Effects of Estrogen on ER, NGF, and ChAT Expression in Cerebellum of Aging Female Sprague-Dawley Rat. Agricultural Sciences in China, 2007, 6(3): 368-374. 34. 曾朝蓉, 岳冬, 孙伟, 胡力文, 石真, 符杰, 龚玉来, 姚晓梅, 熊义英, 陈正礼, 胡延春. MPTP诱导帕金森模型大鼠的血液学及临床病理评价. 成都医学院学报,2020,15(1):23-27. 35.高爽,谭金龙,罗启慧,黄超,刘文涛,陈正礼.大豆异黄酮对油酸致大鼠肝损伤的干预作用.中国细胞生物学学报, 2020, 42(5): 829–838. 36.陈兵,徐婧,罗启慧,黄超,刘文涛,吴洪,陈镜妃,陈苹,高琪,马文静,陈正礼.感染鸭源小鹅瘟病毒QH-L01株樱桃谷雏鸭病理学研究.浙江农业学报, 2018, 30( 6) :932-93837. 37.唐伊,谭金龙,罗启慧,黄超,刘文涛,陈正礼.大豆异黄酮对大鼠骨骼肌纤维组织形态及肌收缩蛋白表达的影响.中国细胞生物学学报, 2018, 40(8): 1319–1325. 38.陈苹,李立科,陈晓林,李一帆,罗启慧,黄超,刘文涛,陈正礼.大豆异黄酮对大鼠肝脏脂肪酸代谢的影响.yl34511线路中心学报,2018,36(2):267-272. 39.陈苹,罗启慧,黄超,李立科,李一帆,陈晓林,刘文涛,陈正礼.大豆异黄酮对健康大鼠肝脏DGAT1、CB1R、FAAH表达的影响.西北农林科技大学报(自然科学版),2018,46(5). 40.夏玉,罗启慧,祝春梅,陈正礼.大豆异黄酮对去卵巢大白鼠垂体雌激素受体和白细胞介素–2表达的影响.湖南农业大学学报(自然科学版) 2018, 44(1):82–87. 41.高琪,罗启慧,曾文,黄超,刘文涛,龚立,陈正礼.高剂量电离辐射对恒河猴器官组织病理改变及相关细胞因子表达的影响.农业生物技术学报,2017, 25(11): 1831-1837. 42.阳丹丹,齐琪,陈正礼,陈兵,黄超,罗启慧,刘文涛.内质网应激调控重楼皂苷I诱导肝癌HepG2细胞凋亡的研究.中国细胞生物学学报,2017, 39(11). 43.陈镜妃,罗启慧,黄超,刘文涛,曾文,高琪,陈苹,陈兵,陈正礼.血管内皮生长因子与色素上皮衍生因子在糖尿病猕猴视网膜病变早期的表达.南方医科大学学报, 2017, 37(9): 1217-1221 44.李立科,史良琴,刘衡,罗启慧,黄超,刘文涛,陈晓林,陈正礼.左旋多巴和氯碘羟喹治疗对帕金森病猕猴血清抗氧化能力的影响.浙江大学学报(农业与生命科学版), 2017, 43(3):371-376. 45. 陈兵,徐婧,黄超,刘文涛,阳丹丹,陈镜妃,马文静,陈正礼,罗启慧.樱桃谷肉鸭源细小病毒QH-L01株的分离鉴定及VP1基因序列分析.中国兽医科学,2017,47(07):909-914 46.陈镜妃,程东静,陈正礼.神经营养因子对糖尿病视网膜病变的治疗研究进展.中华糖尿病杂志,2017,9(6):400-202. . 47.陈苹,罗启慧,黄超,刘文涛,陈镜妃,高琪,曾文,龚立,陈正礼. T1DM猕猴肝中CB1R和GR及FAAH的表达.中国兽医科学2017,47(04):523-528. 48.刘衡,史良琴,李立科,罗启慧,黄超,刘文涛,曾文,陈正礼.帕金森恒河猴血液P53、Bax、Bcl-2、Caspase-3 mRNA的进程性变化.农业生物技术学报,2017, 25(4): 621-627. 49.邹瑶,张露,陈正礼,黄超,刘文涛,罗启慧,徐婧,夏玉,阳丹丹.猴源宋内氏志贺菌的分离鉴定及生物学特性分析.中国兽医科学,2017,47(01):60- 66. 50.李立科,罗启慧,唐秀莹,黄超,陈晓林,刘文涛,陈正礼.大豆异黄酮对肥胖大鼠肠道瘦素介导Janus激酶/信号转导及转录激活因子信号转导通路的影响.动物营养学报,2016,28(8):2448-2457. 51.夏玉,罗启慧,祝春梅,史良琴,陈姗姗,邓娟,邹瑶,程安春,陈正礼.大豆异黄酮对去卵巢大鼠脾脏NGF、IL-2蛋白表达的影响.浙江农业学报, 2016,28(7):1135-1141. 52.陈晓林,罗启慧,唐秀莹,刘芸,李立科,陈正礼. SIF干预肥胖大鼠下丘脑瘦素介导JAK/STAT信号通路的研究.浙江农业学报,2016,28(3):420-427. 53.李立科,罗启慧,唐秀莹,黄超,陈晓林,刘文涛,陈正礼.大豆异黄酮对肥胖大鼠肠道瘦素介导Janus激酶/信号转导及转录激活因子信号转导通路的影响.动物营养学报2016,28(8):2448-2457. 54.崔雨婷,张睿,陈正礼,罗启慧,祝春梅,孙凤娇,陈梦鹿.大鼠自发性乳腺肿瘤中Bax、Bcl-2和Caspase-3的表达.浙江大学学报(农业与生命科学版) ,2016,42(1):119. 55.夏玉,罗启慧,祝春梅,史良琴,陈姗姗,邓娟,邹瑶,程安春,陈正礼.大豆异黄酮对去卵巢大鼠脾脏NGF、IL-2蛋白表达的影响.浙江农业学报,2016,8(7):1135-1141. 56.罗启慧,王承东,李德生,邓林华,李才武,陈正礼,黄超.大熊猫卵巢OB-Rb、NPY的蛋白表达与分布研究.浙江农业报,2016,28(12):2000-2006. 57.马文静,罗启慧,陈姗姗,陈正礼.猕猴脾脏中IL–2蛋白表达的性别差异.湖南农业大学学报(自然科学版),2015, 41(6):651–654.(通讯作者,CSCD收录) 58.张睿,崔雨婷,陈正礼,罗启慧,祝春梅,孙凤娇,陈梦鹿.线粒体凋亡相关因子在大鼠自发性乳腺肿瘤中的表达.中国实验动物学报,2015,23(4):375-381. 59.张芮琪,陈正礼,罗启慧.黄芪多糖干预环磷酰胺所致免疫抑制小鼠的免疫功能.中国实验动物学报2015,23(4):389-394. 60.罗启慧,唐秀莹,陈正礼,汪开毓,王承东,李德生,李才武.大熊猫胃肠道神经肽Y和长型瘦素受体的表达.生物工程学报,2015, 31(8): 1175−1183. 61.罗启慧,刘芸,唐秀莹,陈正礼.大豆异黄酮对肥胖大鼠弓状核及垂体α-MSH、POMC、Ob-Rb表达的影响.华北农学报,2015,30(4):84-89. 62.陈姗姗,罗启慧,曾文,程安春,刘文涛,史良琴,陈正礼.Ⅱ型糖尿病猕猴部分靶器官中Th1 Th2型细胞因子表达分析.浙江大学学报(农业与生命科学版),2015, 41(3):302-308. 63.史良琴,罗启慧,曾文,龚立,程安春,毕凤君,曾利才,陈姗姗,陈正礼. MPTP诱导慢性帕金森病恒河猴模型的初步建立[J].浙江大学学报:农业与生命科学版,2014, 40(3): 257-265. 64.唐秀莹,陈正礼,罗启慧,张小龙.大豆异黄酮对大鼠肠道上皮内淋巴细胞、杯状细胞及瘦素长型受体的影响.浙江大学学报(农业与生命科学版), 2013,39(3),343-350. 65. Qihui Luo, Wen Zeng, Zhengli Chen, Anchun Cheng, Mingshu Wang, Yubo Shen, Chunmei Zhu, Fengjun Bi. The effect of PPARδ agonists (HS00098) on serum lipid profiles in diet-induced obese rhesus monkeys. J. Biomedical Science and Engineering,2012, 5:439-447. 66.陈恋,罗启慧,章瑶,陈正礼,程安春,曾文.感染肺炎链球菌的猕猴消化系统分泌型免疫球蛋白A的表达.浙江大学学报(农业与生命科学版) ,2012, 38(6):675-683. 67.章瑶,罗启慧,陈恋,陈正礼,程安春,曾文.肺炎链球菌感染猕猴肺及气管内分泌型免疫球蛋白A(sIgA)的表达.农业生物技术学报,2012, 20(2),157-164. 68.罗启慧,陈恋,章瑶,陈正礼,程安春,曾文.感染肺炎链球菌猕猴消化系统白细胞介素6的表达观察,兽类学报,2012,32(1):58-66. 69.罗启慧,章瑶,陈恋,陈正礼,曾文,程安春*.肺炎链球菌感染的猕猴肺及气管内IFN‐γ蛋白与mRNA表达,浙江大学学报(农业与生命科学版) ,2012, 38(1):48-54. 70.贾姣,李冰,赖茂银,杨丽莎,陈正礼,程安春,曾文.猕猴自然流产胎儿胸腺白细胞介素2和10的分布与表达.农业生物技术学报,2012, 20(11):1321-1326. 71.陈正礼,祝春梅,罗启慧,潘康成.大豆异黄酮对去卵巢大鼠小脑ERα、NGF、IL-2、AR mRNA表达的影响.浙江大学学报(农业与生命科学版), 2010,36(1):62-68. 72.陈正礼,罗启慧,程安春.大豆异黄酮对去卵巢大鼠脾脏IL-2 mRNA表达的影响.中国农业科学, 2010, 43(9):1948-1953. 73.陈正礼,罗启慧,曾文,程安春.雌激素受体在老年和青年猕猴下丘脑中表达的比较.兽类学报,2010,30 (2):177-181. 74.陈正礼,罗启慧,范光丽.雌激素对大鼠小脑神经元生长发育的影响.浙江大学学报(农业与生命科学版), 2008,34(2):181. 75.祝春梅,陈正礼,曾文,程安春.猕猴脾脏中雌激素受体的表达及性别差异研究.中国兽医学报, 2008,28(10):1239. 76.罗启慧,陈正礼,范光丽.雌激素对去卵巢大鼠小脑ER、ChAT、NGF表大的影响.畜牧兽医学报2007,38(9):959~965.陈正礼,罗启慧,范光丽,阿衣木古丽.雌激素对老年大鼠小脑ER、ChAT、NGF表达的影响.中国农业科学,2006,39(3):627~632. |
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获奖、新药、新品种等 |
1.水禽传染病防控关键技术研究和应用创新团队,神农中华科技优秀创新团队奖,2019. 2.yl34511线路中心本科课堂教学质量奖,特等奖。 3.“三主、三导、三融合” 协同的动医专业创新人才培养模式构建与实践,四川省教学成果二等奖。 4.“开放共享、融合互补”动物解剖及组织胚胎学课程教学改革与实践,校级教学成果一等奖。 5.适应新时代新农科国际视野需求的动物医学类本科人才培养模式创新和实践,四川省教学成果一等奖。 6.动医专业创新人才培养体系构建与实践,校级教学成果一等奖 |
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指导挑战杯、创青春、互联网+等双创项目获省级奖项(近五年,注获奖时间) |
第六届全国大学生动物医学专业(本科)技能大赛,获行业协会、学会国家级特等奖,优秀指导教师,2020。 |
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创新实验、科研兴趣计划项目(近五年,注立项时间) |
1.省级大学生创新性项目,大豆异黄酮对肌肉生长作用的研究,2017; 2.科研兴趣项目,LanCL1蛋白在大熊猫睾丸肿瘤中的作用与氧化应激机制研究,2021; 3.科研兴趣项目,大熊猫肿瘤病理诊断和特异肿瘤标志物检测方法的建立及应用,2021; 4.科研兴趣项目,油酸致大鼠肝损伤病理学变化及大豆异黄酮的干预研究,2018; 5.科研兴趣项目,油酸致大鼠肺损伤病理学变化及大豆异黄酮的干预研究,2018; 6.科研兴趣项目,EMC3在少精弱精病病人精液中的表达情况,2020; 7.科研兴趣项目,Banf2在少精弱精病病人精液中的表达情况,2020。 |
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授权专利、编著教材 |
1.罗启慧.马文静.劳澄婕.陈正礼,黄超,刘文涛,夏玉. 一种慢性食源性帕金森病小鼠模型及其建立方法和应用, 2019-10-21,中国, CN201911002647.7.(专利责任人) 2.罗启慧,史良琴,陈正礼,刘衡,李立科,黄超,刘文涛,方静,唐丽,曾文,龚立.灵长类帕金森病模型行为学评价优化方法.公开(公告)号:CN105878240A).(专利责任人) 3.罗启慧,史良琴,陈正礼,曾文,黄超,龚立,李立科,刘衡,刘文涛,方静,唐丽. 一种慢性进程性帕金森病恒河猴模型的建立.公开(公告)号:CN105662638A).(专利责任人) 4.罗启慧,陈正礼,黄丹凤,程安春,黄超,彭西,方静,唐丽,曾文,龚立. 恒河猴免疫抑制模型的建立.发明专利公开(公告)号: CN105030794A.(专利责任人) 5.罗启慧,陈正礼,曾文,程安春,龚立,毕凤君,曾立才. 一种诱导糖尿病模型的建立方法.发明专利(授权号:Z201310275715.3).(专利责任人) |
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社会服务 |
长期为实验动物与药物评价企业提供技术服务,并为30余家实验动物设施建设提供指导意见,助推四川省实验动物行业健康发展。 |