姓名 |
倪学勤 |
政治面貌 |
中共党员 |
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导师类型 |
博导/硕导 |
办公地点 |
成都校区 6教309 |
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职称/职务 |
教授 |
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电子邮箱 |
xueqinni@foxmail.com |
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研究方向 |
预防兽医学专业动物微生态方向 主要研究家畜家禽、野生动物肠道菌群与功能的解析,肠道原籍益生菌的研究与应用 |
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学术、技术组织任职/头衔 |
中国畜牧兽医学会动物微生态学分会 理事长 四川省学术和技术带头人 |
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教育背景及工作经历 |
教育经历: 1. 2006.04-2007.04,Food Research Program, Agriculture and Agri-food Canada,访问学者 2. 1994.09-1998.12,南京农业大学,yl34511线路中心预防兽医学系,农学博士 3. 1990.09-1993.06,yl34511线路中心,yl34511线路中心预防兽医学系,农学硕士 4. 1986.09-1990.06,yl34511线路中心,兽医系兽医卫生检验专业,农学学士 工作经历: 1. 2010.01-至今,yl34511线路中心,yl34511线路中心,教授,博士生导师 2. 2000.01-2009.12,yl34511线路中心,yl34511线路中心,副教授,硕士生导师 3. 1995.01-1999.12,yl34511线路中心,yl34511线路中心,讲师 4. 1993.07-1994.12,yl34511线路中心,yl34511线路中心,助教 |
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教学课程 |
《动物微生态》《微生态工程》《微生态与健康》 |
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人才培养情况 |
已培养博士生4名、硕士生55余名。 |
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科研项目 (近五年) |
1.国家自然科学基金面上项目(32270561):基于黏附效应研究大熊猫源益生菌对大肠杆菌诱发肠上皮细胞自噬AMPK/mTOR/ULK1通路的干预机制,2023.01-2026.12,主研。 2.四川省科技厅国际合作项目(2021YFH0097):益生菌预防高氟摄入引起记忆损伤的机制研究,2021.04-2023.03,主持。 3.四川省科技计划项目应用基础研究(2021YJ0166):菌-肠-脑轴对精神分裂症康复的调控作用及分子机制研究,2021.04-2023.03,主研。 4.国家自然科学基金面上项目(31970503):大熊猫源植物乳杆菌对菌群源化小鼠肠道炎症的预防与治疗机制研究,2020.01-2023.12,主研。 5.青岛市生物制造行业智库联合基金(QDSWZK202112):仔猪腹泻病新型靶向微生态制剂创制,2021.01-2022.05,主持。 6.成都大熊猫繁育研究基金项目(CPF2017-04):临床死亡金丝猴等几种灵长类动物胃肠道微生物宏基因组与代谢的研究,2018.01-2021.12,主持。 7.四川省国际科技合作与交流研发项目(2018HH0103):益生菌调控亚临床坏死性肠炎肉鸡肠肝循环的分子机制,2017.09-2019.12,主持。 |
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主要论著、 代表性论文 |
以第一或通讯作者发表SCI论文50余篇、中文核心期刊100余篇,参与发表其他论文20余篇。代表性论文如下: 1. Jinge Xin, Bin Zhu, Hesong Wang, Yong Zhang, Ning Sun, Cao Xi, Liqin Zheng, Yanxi Zhou, Jing Fang, Bo Jing, Kangcheng Pan, Yan Zeng, Dong Zeng, Fali Li, Yang Xia, Peng Xu,Xueqin Ni*. Prolonged fluoride exposure induces spatial-memory deficit and hippocampal dysfunction by inhibiting small heat shock protein 22 in mice. Journal of Hazardous Materials, 2023, 456:131595. 2. Lianxin Li, Jinge Xin, Hesong Wang, Yadong Wang, Weiqi Peng, Ning Sun, Haonan Huang, Yanxi Zhou, Xingmei Liu, Yu Lin, Jing Fang, Bo Jing, Kangcheng Pan, Yan Zeng, Dong Zeng, Xiang Qin, Yang Xia,Xueqin Ni*.Fluoride disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated RhoA/ROCK signaling and myosin light chain kinase. Ecotoxicology and Environmental Safety, 2023, 257:114940. 3. Baoxing Gan, Ning Sun, Jing Lai, Zhiqiang Wan, Lianxin Li, Yanyan Wang, Yan Zeng, Dong Zeng, Kangcheng Pan, Jing Fang, Gang Shu, Hesong Wang, Jinge Xin,Xueqin Ni*. Dynamic monitoring of changes in fecal flora of giant pandas in mice: co-occurrence network reconstruction. Microbiology Spectrum, 2022, 6:e0199122. 4. Zhiqiang Wan, Xufei Zhang, Xianhao Jia, Yuhua Qin, Ning Sun, Jinge Xin, Yan Zeng, Bo Jing, Jing Fang, Kangcheng Pan, Dong Zeng, Yang Bai, Hesong Wang, Hailin Ma,Xueqin Ni*.Lactobacillus johnsonii YH1136 plays a protective role against endogenous pathogenic bacteria induced intestinal dysfunction by reconstructing gut microbiota in mice exposed at high altitude. Frontiers in Immunology, 2022, 13:1007737. 5. Ning Sun, Bin Zhu, Jinge Xin, Lianxin Li, Baoxing Gan, Xi Cao, Jing Fang, Kangcheng Pan, Bo Jing, Yan Zeng, Cheng Lv, Ling Zhao, Dong Zeng, Peng Xu*, Hesong Wang* andXueqin Ni*. Psychoactive effects ofLactobacillus johnsoniiBS15 on preventing memory dysfunction induced by acute ethanol exposure through modulating intestinal microenvironment and improving alcohol metabolic level. Frontiers in Microbiology. 2022, 13: 847468. 6. Ying Zhao, Yan Zeng, Dong Zeng, Hesong Wang, Ning Sun, Jinge Xin, Mengjia Zhou, Hanbo Yang, Lei Lei, Hongli Ling, Abdul Khalique, Danish Sharafat, Baoxing Gan, Zhiqiang Wan, Zhipeng Yao, Jing Fang, Kangcheng Pan, Gang Shu, Jing Bo, Dongmei Zhang,Xueqin Ni*. Dietary probiotic supplementation suppresses subclinical necrotic enteritis in broiler chickens in a microbiota-dependent manner. Frontiers in Immunology, 2022, 13:855426. 7. Jie Wang, Bin Wen, Yan Zeng, Hesong Wang, Wei Zhao, Yi Zhou, Lei Liu, Ping Wang, Kangcheng Pan, Bo Jing,Xueqin Ni*, Dong Zeng*. Assessment the role of someBacillus strains in improvement rex rabbits resistance against ETEC challenge. Microbial Pathogenesis, 2022, 165:105477 8. Yi Zhou, Ling Duan, Yan Zeng, Lili Niu, Yang Pu, Jonathan P. Jacobs, Candace Chang, Jie Wang, Abdul Khalique, Kangcheng Pan, Jing Fang, Bo Jing, Dong Zeng*,Xueqin Ni*. The panda-derivedLactobacillus plantarumG201683 alleviates the inflammatory response in DSS-induced panda microbiota- associated mice. Frontiers in Immunology, 2022, 12: 747045. 9. Jie Wang, Yang Pu, Yan Zeng, Yingyi Chen, Wei Zhao, Lili Niu, Benhao Chen, Zihan Yang, Liqian Wu, Kangcheng Pan, Bo Jing, Dong Zeng*,Xueqin Ni*. Multi-functional potential of five lactic acid bacteria strains derived from giant panda (Ailuropoda melanoleuca). Probiotics and Antimicrobial Proteins, 2022. 10.Yan Zeng, Yang Pu, Lili Niu, Jiabo Deng, Dong Zeng, Katherine Ryan Amato, Yang Li, Yi Zhou, Yicen Lin, Jie Wang, Liqian Wu, Benhao Chen, Kangcheng Pan, Bo Jing,Xueqin Ni*. Comparison of gastrointestinal microbiota in golden snub-nosed monkey (Rhinopithecus roxellanae), green monkey (Chlorocebus aethiops sabaeus), and ring-tailed lemur (Lemur catta) by high throughput sequencing. Global Ecology and Conservation, 2022, 33(e01946): 1-12. 11. Ying Zhao, Yan Zeng, Dong Zeng, Hesong Wang, Mengjia Zhou, Ning Sun, Jinge Xin, Abdul Khalique, Danish Sharafat Rajput, Kangcheng Pan, Gang Shu, Bo Jing,Xueqin Ni*. Probiotics and microRNA: their roles in the host-microbe interactions. Frontiers in Microbiology. 2021, 11:604462. 12. Zhiqiang Wan, Ning Sun, Min Luo, Baoxing Gan, Zhipeng Yao, Xi Cao, Hesong Wang, Kangcheng Pan, Gang Shu, Yan Zeng,Dong Zeng*,Xueqin Ni*. Promotion of egg production rate and quality usingLimosilactobacillus orisBSLO 1801, a potential probiotic screened from feces of laying hens with higher egg productive performance. Probiotics and Antimicrobial Proteins, 2021, 1-13. 13. Ying Zhao, et al. Analysis of miRNA expression in the ileum of broiler chickens duringBacillus licheniformisH2 supplementation against subclinical necrotic enteritis. Probiotics and Antimicrobial Proteins, 2021 13(2), 356-366. 14.倪学勤,原籍菌在肉鸡饲料中的研究与应用进展.饲料工业, 2021, 42(5):1-4 |
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获奖、新药、新品种等 |
1.山东省科技进步二等奖,“畜禽肠道健康合生元制品创新技术及产业化”,2018年3月,排名第1。 2. 重庆市科技进步二等奖,“猪用新型产乳酸芽孢杆菌合生元饲料添加剂开发与应用”,2020年7月,排名第10。 |
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创新实验、科研兴趣计划项目(近五年,注立项时间) |
科研兴趣实验6个 |
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授权专利、编著教材 |
授权发明专利: 1.倪学勤 (1/18),一种獭兔源枯草芽孢杆菌及其在提高獭兔生长性能中的应用,ZL201710509085.X,2020.10.23授权。 2.倪学勤 (1/7),一种基于约氏乳酸杆菌BS15的肉鸡饲料及其制备方法,ZL201610344197.X,2020.04.10授权。 3.倪学勤(1/10),约氏乳酸杆菌BS15及其在预防和治疗非酒精性脂肪肝中的应用,ZL 201410156594.5,2016.04.13授权。 4.倪学勤(1/10),枯草芽孢杆菌BS01发酵灵芝孢子粉的制备及其在改善睡眠中的应用,ZL201410152501.1,2017.12.22授权。 5.倪学勤(2/7),枯草芽孢杆菌BS01与灵芝孢子粉的组合物在改善睡眠中的应用,ZL201310301090.3,2016.12.28授权。 6.倪学勤(2/11),一种玉屏风药渣多糖合生元的制备及其在免疫调节中的应用,ZL ZL201510489512.3,2018.06.08授权。 7.倪学勤(4/10),一种大熊猫源植物乳酸杆菌及应用,ZL 201610430331.8,2019.11.08授权。 编著教材: 《细菌耐药危机下的挑战与对策—专家视角》,2019,参编; 《中国人兽共患病学》,2011,参编; 《动物微生态学》,2004,副主编; 《动物微生态研究进展》,2000,副主编 |
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社会服务 |
与微生态制剂、发酵饲料等相关企业合作,开展相关的服务工作。 |